Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX3 | P23760 | 1/20 | 0.39 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17260466 | 0.84 | GDA (0.47) | KDM4ETSHRALDH1A1GAAGDA | |
| SCHEMBL10590403 | 0.77 | NLRP3 (0.40) | KDM4ETSHRALDH1A1NPSR1ALOX15 | |
| SCHEMBL25324519 | 0.77 | RAB9A (0.51) | PAX3FOXO1KDM4ETSHRADORA1 | |
| SCHEMBL17260490 | 0.74 | POLB (0.35) | KDM4ETSHRALDH1A1MEN1LMNA | |
| SCHEMBL537506 | 0.71 | ADORA1 (0.41) | KDM4ENOS1TSHRADORA1ALDH1A1 | |
| SCHEMBL22036469 | 0.70 | ALDH1A1 (0.43) | PAX3FOXO1KDM4ENOS1TSHR | |
| SCHEMBL25322413 | 0.70 | GSK3B (0.37) | KDM4ENOS1TSHRTP53ALDH1A1 | |
| SCHEMBL442818 | 0.68 | NOS1 (0.45) | PAX3FOXO1KDM4ENOS1TSHR | |
| SCHEMBL735411 | 0.67 | GDA (0.72) | GDA | |
| SCHEMBL8886595 | 0.67 | NOS1 (0.38) | PAX3FOXO1KDM4ENOS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59125895-A | — | — | None | — | — | JP | disclosed |
| JP-59106297-A | — | — | None | — | — | JP | disclosed |
| US-20230257413-A1 | ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF | RIKEN GENESIS CO., LTD. (JP) | 2023-08-17 | — | — | US | disclosed |
| EP-4219517-A1 | NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF | Riken Genesis Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023127857-A1 | NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME | 株式会社理研ジェネシス | 2023-07-06 | — | — | WO | disclosed |
| CN-116322706-A | Novel artificial nucleic acid, method for producing same, and use thereof | 株式会社理真思 | 2023-06-23 | — | — | CN | disclosed |
| CN-113646007-A | Novel artificial nucleic acid, method for producing same, and use thereof | 希森美康株式会社 | 2021-11-12 | — | — | CN | disclosed |
| WO-2020203896-A1 | NEW ARTIFICIAL NUCLEIC ACID, PRODUCTION METHOD THEREFOR, AND USE THEREOF | シスメックス株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2006-12-14 | — | — | US | disclosed |
| EP-0463712-A2 | Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections | UNIVERSITY PATENTS, INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990012022-A1 | POLYNUCLEOTIDE PHOSPHORODITHIOATES AS THERAPEUTIC AGENTS FOR RETROVIRAL INFECTIONS | UNIVERSITY PATENTS, INC. (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| EP-0107278-B1 | MOLECULAR CLONING OF THE GENE FOR HUMAN ANTI-HAEMOPHILIC FACTOR IX | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-11-15 | — | — | EP | disclosed |
| EP-0316558-A1 | Factor IX DNA | BTG INTERNATIONAL LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |
| JP-S59125895-A | SYNTHESIS OF HUMAN GROWTH HORMONE GENE | RIKAGAKU KENKYUSHO | 1984-07-20 | — | — | JP | disclosed |
| JP-S59106297-A | SYNTHESIS OF CARBOXY-TERMINATED GENE OF HUMAN GROWTH HORMONE | RIKAGAKU KENKYUSHO | 1984-06-19 | — | — | JP | disclosed |
| EP-0107278-A1 | Molecular cloning of the gene for human anti-haemophilic factor IX | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-05-02 | — | — | EP | disclosed |
| WO-1984000560-A1 | MOLECULAR CLONING OF THE GENE FOR HUMAN ANTI-HAEMOPHILIC FACTOR IX | NAT RES DEV (GB) | 1984-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257413-A1 | ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF | NSUN2, NSUN3, POLRMT | PAX3 1025/4885FOXO1 3288/4885KDM4E 2076/4885 |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, CYP2E1, ADH1C | PAX3 4347/4885FOXO1 350/4885KDM4E 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.