Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890420 | 0.89 | HIF1A (0.55) | CA1CA2RAB9ANPC1HPGD | |
| SCHEMBL8890381 | 0.89 | NPC1 (0.49) | RXRAMRGPRX4RAB9ANPC1HPGD | |
| SCHEMBL28217561 | 0.84 | CA12 (0.57) | RXRAMRGPRX4CA12CA1CA2 | |
| SCHEMBL8891893 | 0.82 | PDE4A (0.57) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL8890296 | 0.81 | ALDH1A1 (0.61) | RXRAMRGPRX4CA12CA1CA2 | |
| SCHEMBL3369018 | 0.81 | CA12 (0.54) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL5467531 | 0.80 | RXRA (0.57) | RXRAMRGPRX4RAB9ANPC1HPGD | |
| SCHEMBL2937821 | 0.80 | PDE4A (0.61) | RXRAMRGPRX4CA12CA1CA2 | |
| SCHEMBL1029034 | 0.79 | SMPD1 (0.75) | RXRAMRGPRX4CA12CA1CA2 | |
| SCHEMBL242563 | 0.79 | MRGPRX4 (0.77) | RXRAMRGPRX4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |