Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550337 | 0.90 | CYP4F2 (0.56) | ALOX5CYP4Z1CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL6583008 | 0.89 | ALOX5 (0.62) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL30303108 | 0.85 | CYP1A2 (0.52) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9121505 | 0.82 | CYP4Z1 (0.53) | ALOX5CYP4Z1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5723918 | 0.82 | CYP1A2 (0.48) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8889417 | 0.81 | TUBB4A (0.58) | ALOX5CYP4Z1CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL20399450 | 0.81 | KAT8 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL1099001 | 0.81 | APP (0.50) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8888747 | 0.80 | APP (0.57) | ALOX5ALDH1A1 | |
| SCHEMBL20399514 | 0.79 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |