Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901541 | 0.92 | DHODH (0.34) | PLA2G2ASMN1; SMN2PTGDR2DHODHPDE2A | |
| SCHEMBL8892441 | 0.92 | DHODH (0.34) | SMN1; SMN2DHODHPDE2ANR1H4CRACR2A | |
| SCHEMBL8892787 | 0.91 | HPGD (0.36) | PLA2G2ASMN1; SMN2PTGDR2DHODHPDE2A | |
| SCHEMBL8891643 | 0.87 | CCR5 (0.35) | PLA2G2APTGDR2DHODHTAS1R3TAS1R1 | |
| SCHEMBL8890676 | 0.85 | ALDH1A1 (0.35) | PLA2G2ASMN1; SMN2PTGDR2TAS1R3TAS1R1 | |
| SCHEMBL8890836 | 0.85 | TAS1R3 (0.33) | PLA2G2APTGDR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8890301 | 0.85 | TAS1R3 (0.33) | PLA2G2ASMN1; SMN2PTGDR2DHODHTAS1R3 | |
| SCHEMBL8891039 | 0.84 | TAS1R3 (0.34) | PLA2G2APTGDR2DHODHTAS1R3TAS1R1 | |
| SCHEMBL8891638 | 0.84 | ALOX15 (0.36) | PLA2G2ASMN1; SMN2PTGDR2TAS1R3TAS1R1 | |
| SCHEMBL8893223 | 0.82 | NAMPT (0.32) | PTGDR2TAS1R3TAS1R1TAS1R2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |