Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892441 | 0.94 | DHODH (0.34) | DHODHPDE2ACRACR2ALMNARUVBL1 | |
| SCHEMBL8892787 | 0.93 | HPGD (0.36) | DHODHPDE2ACRACR2ALMNATP53 | |
| SCHEMBL8891005 | 0.92 | PLA2G2A (0.36) | DHODHPDE2ACRACR2ASMN1; SMN2PLA2G2A | |
| SCHEMBL8891580 | 0.88 | PTGS1 (0.35) | DHODHPDE2ACNR2CNR1DPP4 | |
| SCHEMBL8890688 | 0.88 | LMNA (0.34) | DHODHPDE2ACNR2CNR1DPP4 | |
| SCHEMBL8890084 | 0.86 | RUVBL1 (0.32) | DHODHPDE2ACNR2CNR1DPP4 | |
| SCHEMBL8892550 | 0.80 | ALDH1A1 (0.34) | DHODHPDE2ALMNAALDH1A1HPGD | |
| SCHEMBL8893301 | 0.80 | TBXA2R (0.37) | PDE2AALDH1A1HPGDPTGDR2KDM4E | |
| SCHEMBL8891643 | 0.79 | CCR5 (0.35) | DHODHPDE2APLA2G2APTGDR2 | |
| SCHEMBL8891456 | 0.78 | ALDH1A1 (0.35) | PDE2AALDH1A1HPGDPTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |