Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890306 | 0.88 | L3MBTL1 (0.50) | KDM4EMAPTPOLBMAPK14SMO | |
| SCHEMBL17844308 | 0.86 | KDM4E (0.61) | KDM4EMAPTSYKAURKBINCENP | |
| SCHEMBL8890013 | 0.86 | KDM4E (0.61) | KDM4EMAPTSYKAURKBINCENP | |
| SCHEMBL8891783 | 0.81 | RAB9A (0.50) | KDM4EMAPTSYKAURKBINCENP | |
| SCHEMBL15062003 | 0.79 | SYK (0.46) | KDM4EMAPTSYKSMN1; SMN2 | |
| SCHEMBL8892009 | 0.79 | PDE4D (0.55) | KDM4EMAPK14SMO | |
| SCHEMBL1122621 | 0.78 | PKM (0.63) | POLBCYP1A2CYP2C19SMN1; SMN2PARP10 | |
| SCHEMBL3778535 | 0.77 | KMT2A (0.58) | KDM4EPOLBCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL12301168 | 0.77 | CA12 (0.47) | MAPTSYKCYP2C19SMN1; SMN2TSHR | |
| SCHEMBL27990964 | 0.77 | KDM4E (0.46) | KDM4EMAPTSYKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |