SCHEMBL8892523

SCHEMBL8892523

CCS(=O)(=O)c1ccc(C(=O)c2cnoc2C2CC2)c(Cc2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 1/20 0.36
CCR5 P51681 1/20 0.35
CYP2C9 P11712 1/20 0.35
RORC P51449 3/20 0.34
TRPM8 Q7Z2W7 2/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
MBTD1 Q05BQ5 1/20 0.33
L3MBTL3 Q96JM7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8890658 0.91 PTGS2 (0.40) CCR5CYP2C9PTGS1PTGS2ALDH1A1
SCHEMBL8891642 0.83 ALDH1A1 (0.39) TRPM8PTGS1PTGS2ALDH1A1KMT2A
SCHEMBL8889447 0.83 CCR5 (0.35) CCR5CYP2C9ALDH1A1MBTD1L3MBTL3
SCHEMBL8890374 0.82 CCR5 (0.36) CCR5CYP2C9ALDH1A1MBTD1L3MBTL3
SCHEMBL8889700 0.82 TSHR (0.42) CCR5CYP2C9ALDH1A1KMT2AS1PR1
SCHEMBL8890712 0.82 KDM4E (0.34) PTGS1PTGS2
SCHEMBL8489354 0.82 THRB (0.37) ALDH1A1
SCHEMBL8892121 0.82 TBXA2R (0.36) ALDH1A1
SCHEMBL8891694 0.82 CCR5 (0.35) CCR5CYP2C9ALDH1A1MBTD1L3MBTL3
SCHEMBL8891282 0.81 HPGD (0.36) CCR5ALDH1A1KMT2AMBTD1L3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997028136-A1 BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1997-08-07 WO disclosed