Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792458 | 0.90 | FAAH (0.48) | PAOXDNM1DGKATHRATHRB | |
| SCHEMBL889254 | 0.90 | FAAH (0.48) | PAOXDNM1DGKATHRATHRB | |
| SCHEMBL12792529 | 0.90 | FAAH (0.48) | PAOXDNM1DGKATHRATHRB | |
| SCHEMBL889280 | 0.89 | KDM4E (0.38) | PAOXDNM1LTA4HDGKAEPHX2 | |
| SCHEMBL29761176 | 0.86 | FAAH (0.50) | PAOXDNM1DGKATHRATHRB | |
| SCHEMBL19976134 | 0.86 | LTA4H (0.39) | PAOXDNM1LTA4HDGKAALDH1A1 | |
| SCHEMBL9972626 | 0.85 | FAAH (0.49) | PAOXDNM1DGKATHRATHRB | |
| SCHEMBL889250 | 0.85 | DGKA (0.48) | PAOXDNM1LTA4HDGKAALDH1A1 | |
| SCHEMBL889193 | 0.85 | DNM1 (0.49) | DNM1DGKAALDH1A1THRATHRB | |
| SCHEMBL889304 | 0.84 | ALDH1A1 (0.38) | PAOXDNM1DGKAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | FCGRT, MYD88, C3AR1 | PAOX 1247/4885DNM1 4279/4885LTA4H 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.