Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203147 | 0.91 | RET (0.33) | MAPTRETKDRL3MBTL1FFAR1 | |
| SCHEMBL6200639 | 0.77 | RET (0.33) | MAPTRETKDRGPR55 | |
| SCHEMBL8202222 | 0.73 | CNR1 (0.38) | SMN1; SMN2ALDH1A1GPR55 | |
| SCHEMBL8893617 | 0.73 | CNR1 (0.34) | L3MBTL1GPR55 | |
| SCHEMBL8193843 | 0.72 | MMP1 (0.34) | GPR55 | |
| SCHEMBL8200735 | 0.72 | L3MBTL1 (0.37) | L3MBTL1GPR55BCHEACHE | |
| SCHEMBL8204279 | 0.70 | ALDH1A1 (0.39) | MAPTSMN1; SMN2ALDH1A1NPSR1GPR55 | |
| SCHEMBL349616 | 0.70 | DDR1 (0.34) | — | |
| SCHEMBL13620295 | 0.68 | DDR1 (0.31) | — | |
| SCHEMBL12196413 | 0.67 | CCR2 (0.36) | MAPTSMN1; SMN2ALDH1A1NPSR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033882-A1 | NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE | G.D. SEARLE AND CO. (US) | 1997-09-18 | — | — | WO | disclosed |