Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201251 | 0.89 | LMNA (0.35) | LMNAHTTCNR1ALDH1A1MAPT | |
| SCHEMBL8893617 | 0.75 | CNR1 (0.34) | LMNAHTTCNR1CNR2GPR18 | |
| SCHEMBL27510398 | 0.74 | APOBEC3G (0.38) | LMNAHTTPTGS2HPGDEPHX2 | |
| SCHEMBL6201198 | 0.74 | AR (0.36) | LMNAHTTCNR1CNR2GPR18 | |
| SCHEMBL8026003 | 0.73 | CTSK (0.40) | LMNAALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8892569 | 0.73 | L3MBTL1 (0.33) | LMNAHTTCNR1CNR2GPR18 | |
| SCHEMBL27390274 | 0.71 | MEN1 (0.32) | LMNAPTGS2ALDH1A1 | |
| SCHEMBL8201722 | 0.71 | ALDH1A1 (0.41) | LMNAHTTPTGS2ALDH1A1MAPT | |
| SCHEMBL27393019 | 0.70 | LTB4R (0.37) | LMNACNR1ALDH1A1 | |
| SCHEMBL6224286 | 0.68 | RAB9A (0.36) | PTGS2ALDH1A1HPGDCNR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033882-A1 | NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE | G.D. SEARLE AND CO. (US) | 1997-09-18 | — | — | WO | disclosed |