Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892670 | 0.74 | NPC1 (0.40) | HPGDSMN1; SMN2MEN1KMT2AFKBP1A | |
| SCHEMBL8892667 | 0.73 | HPGD (0.37) | HPGDSMN1; SMN2MEN1KMT2AFKBP1A | |
| SCHEMBL8893076 | 0.72 | ITGB3 (0.45) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8891945 | 0.71 | PRSS1 (0.49) | F10POLBITGB3PRSS1PRSS2 | |
| SCHEMBL8892614 | 0.66 | HPGD (0.43) | HPGDSMN1; SMN2MEN1KMT2AFKBP1A | |
| SCHEMBL7462288 | 0.63 | LMNA (0.40) | MEN1KMT2AMETAP2 | |
| SCHEMBL8315856 | 0.63 | GRM2 (0.48) | F10 | |
| SCHEMBL8892340 | 0.62 | MEN1 (0.42) | MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8893748 | 0.62 | HPGD (0.44) | HPGDSMN1; SMN2CYP2C19F10ITGB3 | |
| SCHEMBL7458570 | 0.62 | NAMPT (0.43) | SMN1; SMN2MEN1KMT2ACYP2C19F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |