Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8892900

CC(=O)Nc1ccc(C(=O)O)cc1-n1cc(-c2ccco2)nc1N.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.43
ADORA1 P30542 4/20 0.43
ADORA2B P29275 2/20 0.43
ADORA3 P0DMS8 1/20 0.43
PTGS1 P23219 2/20 0.40
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
NSD2 O96028 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
THRB P10828 1/20 0.38
PABPC1 P11940 1/20 0.38
TNNI3 P19429 1/20 0.38
TNNT2 P45379 1/20 0.38
TNNC1 P63316 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892526 0.94 ADORA3 (0.47) ADORA2AADORA1ADORA2BADORA3PTGS1
SCHEMBL8892913 0.87 ADORA2A (0.41) ADORA2AADORA1ADORA2BADORA3PTGS1
Trifluoroacetic Acid SCHEMBL8901207 0.86 ALDH1A1 (0.40) ADORA2AADORA1ADORA2BADORA3MAPT
Trifluoroacetic Acid SCHEMBL8894608 0.82 ADORA3 (0.40) ADORA3MAPTMEN1ALDH1A1GAA
Trifluoroacetic Acid SCHEMBL8894379 0.82 NEU3 (0.33) MAPTMEN1ALDH1A1POLBGAA
Trifluoroacetic Acid SCHEMBL8891099 0.81 ADORA3 (0.41) ADORA3MAPTMEN1ALDH1A1POLB
SCHEMBL8901022 0.79 ADORA3 (0.44) ADORA2AADORA1ADORA2BADORA3MAPT
Trifluoroacetic Acid SCHEMBL8902577 0.78 KEAP1 (0.42) MAPTMEN1ALDH1A1KMT2ATP53
SCHEMBL8891085 0.76 TLR8 (0.41) ADORA2AADORA1ADORA2BADORA3MAPT
SCHEMBL8891817 0.76 ADORA3 (0.44) ADORA3MAPTMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033872-A1 ANTI-VIRAL 4-ACYLAMINO-3-[IMIDAZOL-I-YL]-BENZOIC ACID DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1997-09-18 WO disclosed