Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891702 | 0.93 | ALDH1A1 (0.48) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8891930 | 0.92 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8892236 | 0.91 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8894142 | 0.91 | LMNA (0.48) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8892364 | 0.86 | KEAP1 (0.38) | POLBALDH1A1TBXA2RKEAP1NFE2L2 | |
| SCHEMBL8893264 | 0.86 | NPC1 (0.38) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8890314 | 0.85 | L3MBTL1 (0.41) | POLBALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8893258 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8892041 | 0.84 | ALDH1A1 (0.48) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8892376 | 0.83 | NPC1 (0.36) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |