Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894685 | 0.79 | CXCR3 (0.47) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL7706497 | 0.74 | OPRL1 (0.54) | OPRL1OPRM1OPRK1OPRD1BACE1 | |
| SCHEMBL14573344 | 0.73 | SLC6A9 (0.61) | OPRL1OPRM1 | |
| SCHEMBL8176746 | 0.73 | SIGMAR1 (0.62) | OPRL1OPRM1OPRK1 | |
| SCHEMBL7706380 | 0.71 | DRD4 (0.50) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL7701290 | 0.70 | LMNA (0.50) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL7701370 | 0.70 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL5556020 | 0.70 | DRD2 (0.47) | OPRL1OPRM1OPRK1OPRD1BACE1 | |
| SCHEMBL20187119 | 0.70 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL16876782 | 0.70 | CHRNA7 (0.47) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610142-A | Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids | SCIOS INC. (US) | 1997-03-11 | — | — | US | disclosed |