Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800106 | 0.85 | CYP4A11 (0.40) | MEN1KMT2A | |
| SCHEMBL8893537 | 0.83 | LDHA (0.44) | ALDH1A1HTTSMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL25609121 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL29765181 | 0.81 | L3MBTL1 (0.41) | ALDH1A1HTTSMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL21741216 | 0.81 | L3MBTL1 (0.41) | ALDH1A1HTTSMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL25609123 | 0.81 | NR1D1 (0.43) | ALDH1A1HTTSMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL25448644 | 0.80 | HTT (0.49) | ALDH1A1HTTSMN1; SMN2L3MBTL1NR1D1 | |
| SCHEMBL11579749 | 0.80 | LDHA (0.43) | ALDH1A1HTTSMN1; SMN2L3MBTL1NR1D1 | |
| SCHEMBL10519344 | 0.80 | LDHA (0.43) | ALDH1A1HTTSMN1; SMN2L3MBTL1NR1D1 | |
| SCHEMBL11400130 | 0.80 | LDHA (0.43) | ALDH1A1HTTSMN1; SMN2L3MBTL1NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |