Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893416 | 0.87 | PPARA (0.42) | PPARAPPARGHPGDALDH1A1RARB | |
| SCHEMBL8895341 | 0.81 | CYP2C19 (0.36) | ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL7926899 | 0.68 | CDK1 (0.40) | PPARAPPARGHPGDALDH1A1RARB | |
| SCHEMBL11554392 | 0.67 | ALDH1A1 (0.44) | PPARAHPGDALDH1A1HSD17B10NPC1 | |
| SCHEMBL5598883 | 0.67 | ALOX5 (0.43) | PPARAPPARGALOX5 | |
| SCHEMBL9751110 | 0.66 | TRPV1 (0.48) | PPARAPPARGHPGDALDH1A1HSD17B10 | |
| SCHEMBL8710220 | 0.65 | SKP2 (0.37) | PPARAPPARGHPGDLTA4HNPC1 | |
| SCHEMBL14975192 | 0.65 | PPARA (0.45) | PPARAPPARGHPGDALDH1A1NPC1 | |
| SCHEMBL10897372 | 0.65 | ALDH1A1 (0.54) | PPARAHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL10897815 | 0.65 | CA12 (0.51) | HPGDALDH1A1HSD17B10KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |