Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891702 | 0.92 | ALDH1A1 (0.48) | LMNAMAPK1SMN1; SMN2BMPR1BPLK4 | |
| SCHEMBL8890655 | 0.91 | LMNA (0.46) | LMNAMAPK1SMN1; SMN2BMPR1BPLK4 | |
| SCHEMBL8893099 | 0.91 | POLB (0.41) | LMNAMAPK1SMN1; SMN2BMPR1BPLK4 | |
| SCHEMBL8891307 | 0.90 | LMNA (0.46) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8893264 | 0.88 | NPC1 (0.38) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8892376 | 0.86 | NPC1 (0.36) | LMNAMAPK1SMN1; SMN2BMPR1BPLK4 | |
| SCHEMBL8891705 | 0.84 | ALDH1A1 (0.39) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8891064 | 0.84 | L3MBTL1 (0.43) | LMNAMAPK1SMN1; SMN2POLBPTPRB | |
| SCHEMBL8893258 | 0.83 | ALDH1A1 (0.47) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8892041 | 0.82 | ALDH1A1 (0.48) | LMNAMAPK1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |