Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893995 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891944 | 0.91 | ABCC9 (0.48) | ALDH1A1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891439 | 0.90 | PTPRB (0.40) | KMT2ALMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8892364 | 0.89 | KEAP1 (0.38) | ALDH1A1KMT2APOLBMEN1HTT | |
| SCHEMBL8892494 | 0.87 | HTT (0.38) | ALDH1A1KMT2ACNR1MAPTKDM4E | |
| SCHEMBL8892055 | 0.85 | HTT (0.36) | ALDH1A1KMT2ALMNACNR1MAPT | |
| SCHEMBL8894142 | 0.84 | LMNA (0.48) | ALDH1A1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891064 | 0.84 | L3MBTL1 (0.43) | KMT2ALMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8893753 | 0.84 | POLB (0.41) | ALDH1A1KMT2ACNR1L3MBTL1POLB | |
| SCHEMBL8890408 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KMT2ACNR1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |