Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442988 | 1.00 | CTSS (0.39) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL9750052 | 0.92 | CTSS (0.39) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL9749523 | 0.91 | CACNA1B (0.43) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL9876609 | 0.91 | REN (0.44) | CTSSCTSKRENCYP3A4KMT2A | |
| SCHEMBL8852922 | 0.90 | CACNA1B (0.47) | CTSSCTSKCACNA1BRENMEN1 | |
| SCHEMBL7425454 | 0.89 | CTSK (0.43) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL9749944 | 0.87 | CTSS (0.37) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL7426539 | 0.87 | CTSS (0.45) | CTSSCTSKSCN9AMEN1LMNA | |
| SCHEMBL9876362 | 0.86 | CTSS (0.41) | CTSSCTSKCACNA1BRENCYP3A4 | |
| SCHEMBL10762000 | 0.86 | CTSS (0.41) | CTSSCTSKCACNA1BRENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |