Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444348 | 1.00 | DPEP1 (0.44) | DPEP1PPARGPPARAEPHX2DPP4 | |
| SCHEMBL7430616 | 0.88 | METAP2 (0.45) | DPEP1PPARGDPP4FAPDPP8 | |
| SCHEMBL7430623 | 0.88 | METAP2 (0.45) | DPEP1PPARGDPP4FAPDPP8 | |
| SCHEMBL8894607 | 0.86 | MME (0.43) | PPARGRENMETAP2METAP1LTA4H | |
| SCHEMBL8894601 | 0.86 | MME (0.43) | PPARGRENMETAP2METAP1LTA4H | |
| SCHEMBL8892316 | 0.84 | PPARA (0.49) | PPARGPPARAEPHX2DPP4GRB2 | |
| SCHEMBL7436178 | 0.83 | EPHX1 (0.42) | PPARGDPP4FAPDPP8DPP9 | |
| SCHEMBL7433904 | 0.83 | LDHA (0.45) | PPARGEPHX2DPP4FAPDPP8 | |
| SCHEMBL7433911 | 0.83 | LDHA (0.45) | PPARGEPHX2DPP4FAPDPP8 | |
| SCHEMBL7436183 | 0.83 | EPHX1 (0.42) | PPARGDPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |