Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552234 | 0.73 | CES1 (0.56) | MAOBMAOAALDH1A1 | |
| SCHEMBL8910238 | 0.70 | GPR84 (0.49) | MAOBMAOAALDH1A1GPR84 | |
| SCHEMBL27772234 | 0.69 | NPC1 (0.63) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL25921175 | 0.66 | BRS3 (0.50) | MAOBMAOANR1H3PARK7ALDH1A1 | |
| SCHEMBL8034832 | 0.64 | MAOA (0.51) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL28178421 | 0.64 | PARP11 (0.55) | MAOBMAOACA12CA9PARP11 | |
| SCHEMBL8184437 | 0.63 | DRD2 (0.50) | MAOBMAOA | |
| SCHEMBL7136305 | 0.62 | ALDH1A1 (0.58) | MAOBMAOAHDAC1ALDH1A1 | |
| SCHEMBL55138 | 0.62 | MAOB (0.72) | MAOBMAOACA1CA2ALDH1A1 | |
| Methane SCHEMBL8601392 | 0.62 | ALDH1A1 (0.65) | MAOBMAOACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048698-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |