Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.46 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892973 | 0.92 | CTSS (0.52) | CTSLCTSSPSMB5PSMB11PSMA7 | |
| SCHEMBL7432162 | 0.86 | CTSB (0.52) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL6429766 | 0.83 | CTSS (0.52) | CTSLCTSSPSMB5PSMB11PSMA7 | |
| SCHEMBL7404833 | 0.81 | MMP8 (0.56) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL4311269 | 0.81 | MMP8 (0.56) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL30051590 | 0.80 | ACE (0.64) | CTSD | |
| SCHEMBL7514990 | 0.79 | CTSS (0.51) | CTSLCTSSPSMB5CTSB | |
| SCHEMBL8894263 | 0.78 | CTSS (0.47) | CTSLCTSSPSMB5PSMB11PSMA7 | |
| SCHEMBL30051904 | 0.78 | MME (0.57) | CTSD | |
| SCHEMBL7388307 | 0.77 | CTSK (0.51) | CTSLCTSDCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |