Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388307 | 0.92 | CTSK (0.51) | CTSBCTSSCTSLCTSKCASP3 | |
| SCHEMBL8893516 | 0.89 | CASP3 (0.51) | CTSBCTSSCTSLCTSKREN | |
| SCHEMBL7391841 | 0.88 | CTSK (0.56) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL8894828 | 0.86 | CTSL (0.48) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL7434982 | 0.85 | CTSS (0.58) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL8892749 | 0.84 | CTSK (0.55) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL8893671 | 0.84 | CTSS (0.55) | CTSBCTSSCTSLCTSK | |
| SCHEMBL8895231 | 0.84 | CTSS (0.55) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7438999 | 0.83 | CTSS (0.55) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL7439440 | 0.81 | CTSB (0.48) | CTSBCTSSCTSLCTSKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |