Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.47 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.47 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.47 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894828 | 0.92 | CTSL (0.48) | CTSSCTSLCTSBPSMB11PSMA7 | |
| SCHEMBL6429766 | 0.87 | CTSS (0.52) | CTSSCTSLCTSBPSMB11PSMA7 | |
| SCHEMBL8894263 | 0.86 | CTSS (0.47) | CTSSCTSLCTSBPSMB11PSMA7 | |
| SCHEMBL7388307 | 0.85 | CTSK (0.51) | CTSSCTSLCTSB | |
| SCHEMBL7514990 | 0.84 | CTSS (0.51) | CTSSCTSLCTSBPSMB5 | |
| SCHEMBL4311269 | 0.83 | MMP8 (0.56) | CTSSCTSLCTSBTACR2MMP8 | |
| SCHEMBL7404833 | 0.83 | MMP8 (0.56) | CTSSCTSLCTSBTACR2MMP8 | |
| SCHEMBL8893516 | 0.82 | CASP3 (0.51) | CTSSCTSLCTSB | |
| SCHEMBL29350741 | 0.79 | FNTA (0.56) | — | |
| SCHEMBL8895445 | 0.78 | CTSB (0.47) | CTSSCTSLCTSBPSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0626178-A1 | Use of inhibitors of HIV-protease for the treatment of tumorous diseases | CIBA-GEIGY AG (CH) | 1994-11-30 | — | — | EP | disclosed |