Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566182 | 1.00 | L3MBTL1 (0.50) | L3MBTL1NPSR1KCNH2SRCCA1 | |
| SCHEMBL8521617 | 0.94 | L3MBTL1 (0.49) | L3MBTL1NPSR1KCNH2SRCCA1 | |
| SCHEMBL10408346 | 0.81 | CA2 (0.51) | L3MBTL1SRCCA1CA2CA12 | |
| SCHEMBL122230 | 0.81 | SRC (0.58) | L3MBTL1NPSR1SRCTDP1TP53 | |
| SCHEMBL23788261 | 0.80 | L3MBTL1 (0.42) | L3MBTL1KCNH2SRCTDP1PKM | |
| SCHEMBL124095 | 0.80 | CA1 (0.54) | L3MBTL1NPSR1KCNH2SRCCA1 | |
| Phosphoric Acid Diethyl Ester Phenyl Ester SCHEMBL133234 | 0.80 | CA1 (0.59) | L3MBTL1NPSR1KCNH2SRCCA1 | |
| SCHEMBL9463259 | 0.80 | LTA4H (0.46) | — | |
| Methylene Chloride SCHEMBL29220060 | 0.79 | SRC (0.52) | L3MBTL1SRCTDP1MEN1HTT | |
| SCHEMBL8519322 | 0.79 | TSHR (0.53) | L3MBTL1SRCTDP1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | AMPLYX PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| CN-1882629-A | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORP (US) | 2006-12-20 | — | — | CN | disclosed |
| US-5677281-A | ADMINISTERING ARALKYLPHOSPHONYL TRIPEPTIDE TO INHIBIT SPECIFIED ENDOPEPTIDASES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0278661-A1 | A thiophosphoric acid ester as an insecticide, nematocide and acaricide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4376064-A | OXYGENATED COMPOUND OF PHOSPHORUS | STANDARD OIL CO. (INDIANA) (US) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | ERG28, PDXK, PAH | L3MBTL1 4607/4885NPSR1 3544/4885KCNH2 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.