Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9097651 | 0.80 | PTGES (0.41) | PTGESSMN1; SMN2KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8894739 | 0.80 | SLC9A1 (0.54) | — | |
| SCHEMBL8896076 | 0.79 | VCAM1 (0.48) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL15970647 | 0.78 | ALDH1A1 (0.46) | PTGESALDH1A1L3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL8896458 | 0.77 | VCAM1 (0.49) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL8057356 | 0.75 | VCAM1 (0.52) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL27363242 | 0.75 | FFAR1 (0.52) | ALDH1A1SMN1; SMN2NPSR1ATMKMT2A | |
| SCHEMBL8896168 | 0.75 | PTGS2 (0.47) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL8894967 | 0.74 | VCAM1 (0.51) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL11230748 | 0.74 | KCNH2 (0.44) | PTGESALDH1A1ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693672-A | 3,4,5-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5670544-A | ANTIISCHEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |