Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897474 | 0.93 | PPARG (0.36) | PPARGPTGESALOX5PPARAACE | |
| SCHEMBL8895820 | 0.83 | ACE (0.41) | ACETSHR | |
| SCHEMBL8613299 | 0.80 | FOLH1 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL8897470 | 0.75 | CTSL (0.43) | ACESMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8895311 | 0.75 | CTSL (0.46) | PPARGPPARAACESMN1; SMN2KMT2A | |
| SCHEMBL8896571 | 0.75 | CTSL (0.46) | PPARGPPARAACESMN1; SMN2KMT2A | |
| SCHEMBL8896188 | 0.74 | CTSL (0.46) | — | |
| SCHEMBL8896183 | 0.74 | CTSL (0.46) | — | |
| SCHEMBL8896829 | 0.74 | PPARG (0.48) | PPARGPPARASMN1; SMN2TSHRKMT2A | |
| SCHEMBL8897280 | 0.70 | PPARG (0.45) | PPARGPPARASMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |