Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897073 | 0.84 | PKM (0.45) | HDAC3HDAC1HDAC2CNR2ALDH1A1 | |
| SCHEMBL8899809 | 0.83 | MAPT (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL8897989 | 0.73 | MAPT (0.46) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL9679522 | 0.72 | ALDH1A1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL9681277 | 0.72 | GAA (0.46) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL9679885 | 0.71 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL6026322 | 0.69 | CYP1A2 (0.41) | MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8898460 | 0.69 | MAPT (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL8898466 | 0.68 | TP53 (0.40) | HDAC3HDAC1HDAC2HDAC8CNR2 | |
| SCHEMBL8898434 | 0.68 | TSHR (0.44) | ALDH1A1LMNAMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |