Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680485 | 0.77 | ALDH1A1 (0.53) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL24178666 | 0.76 | SMN1; SMN2 (0.63) | GAAALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL8899809 | 0.76 | MAPT (0.44) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL8897989 | 0.74 | MAPT (0.46) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL855138 | 0.73 | ALDH1A1 (0.61) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL9681707 | 0.72 | HDAC1 (0.49) | ALDH1A1MAPTHPGDHDAC1HDAC6 | |
| SCHEMBL8897630 | 0.72 | HDAC3 (0.41) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL5949981 | 0.71 | MAPT (0.59) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL194873 | 0.71 | ALDH1A1 (0.59) | GAAALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL9681004 | 0.71 | RAB9A (0.53) | GAAALDH1A1MAPTHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |