Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899809 | 0.85 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL8898434 | 0.84 | TSHR (0.44) | CYP1A2CYP2C19SMN1; SMN2CES1NPC1 | |
| SCHEMBL8898410 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP2C19LSSSMN1; SMN2CES2 | |
| SCHEMBL8898143 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL3432893 | 0.81 | LMNA (0.33) | CYP1A2RAB9AMAPTCA1CA2 | |
| SCHEMBL3424272 | 0.79 | CYP1A2 (0.39) | CYP1A2CYP2C19LSSSMN1; SMN2RIPK1 | |
| SCHEMBL4650902 | 0.76 | GSK3B (0.46) | SMN1; SMN2PTPN1NPC1RAB9AMAPT | |
| SCHEMBL31042982 | 0.76 | PLOD2 (0.43) | CYP1A2CYP2C19SMN1; SMN2CES2CES1 | |
| SCHEMBL6026394 | 0.75 | THRA (0.39) | NPC1RAB9AKMT2A | |
| SCHEMBL2697072 | 0.75 | MLYCD (0.44) | CYP2C19SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177182-B1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SC HOLDING AG (CH) | 2006-11-29 | — | — | EP | disclosed |
| US-6673850-B1 | ODORLESS PHOTOINITIATOR COMPOUNDS HAVING CHAIN TRANSFER GROUPS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-06 | — | — | US | disclosed |
| EP-1177182-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | Ciba SC Holding AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068218-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-16 | — | — | WO | disclosed |
| US-6022906-A | α-aminoacetophenone photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |