Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900736 | 1.00 | RELA (0.58) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL8902315 | 0.94 | RELA (0.51) | RELAKDM4EMAPTSMN1; SMN2NFE2L2 | |
| SCHEMBL8900320 | 0.94 | RELA (0.51) | RELAKDM4EMAPTSMN1; SMN2NFE2L2 | |
| SCHEMBL11102794 | 0.87 | TRPA1 (0.58) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL719415 | 0.84 | KMT2A (0.73) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL719416 | 0.84 | KMT2A (0.73) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL8900000 | 0.82 | KMT2A (0.56) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL8901405 | 0.82 | KMT2A (0.56) | RELAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL8900072 | 0.81 | NFE2L2 (0.59) | KDM4EMAPTSMN1; SMN2NFE2L2CYP19A1 | |
| SCHEMBL8901624 | 0.81 | NFE2L2 (0.59) | KDM4EMAPTSMN1; SMN2NFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |