Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902315 | 1.00 | RELA (0.51) | RELAMAOBBCHEFOSJUN | |
| SCHEMBL8900736 | 0.94 | RELA (0.58) | RELAMAOBNFE2L2CYP19A1NQO2 | |
| SCHEMBL8899878 | 0.94 | RELA (0.58) | RELAMAOBNFE2L2CYP19A1NQO2 | |
| SCHEMBL8900072 | 0.87 | NFE2L2 (0.59) | MAOBBCHENFE2L2ABL1BCR | |
| SCHEMBL8901624 | 0.87 | NFE2L2 (0.59) | MAOBBCHENFE2L2ABL1BCR | |
| SCHEMBL414231 | 0.86 | MAPT (0.43) | MAOBBCHEFOSJUNALDH1A1 | |
| SCHEMBL19320327 | 0.79 | RXRA (0.51) | — | |
| SCHEMBL8899998 | 0.79 | KDM4E (0.50) | RELAMAOBBCHEFOSJUN | |
| SCHEMBL9245881 | 0.79 | KDM4E (0.50) | RELAMAOBBCHEFOSJUN | |
| SCHEMBL13135118 | 0.79 | MTNR1B (0.57) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |