Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899510 | 0.89 | SMN1; SMN2 (0.63) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL8889557 | 0.89 | MAPT (0.65) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL8901131 | 0.88 | MAPT (0.62) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL5208862 | 0.84 | MAPT (0.51) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL12171483 | 0.82 | MAPT (0.67) | MAPTHSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8898765 | 0.82 | ALOX15 (0.65) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL5206342 | 0.80 | RAB9A (0.64) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL8889796 | 0.80 | THRB (0.59) | MAPTMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL8901510 | 0.79 | TPH1 (0.58) | MAPTHSD17B10ALOX15CASP1CASP7 | |
| SCHEMBL8898716 | 0.78 | NPC1 (0.60) | MAPTHSD17B10MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |