Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441289 | 0.89 | CYP1A2 (0.43) | TAS1R3TAS1R1TAS1R2POLLKMT2A | |
| SCHEMBL8900041 | 0.79 | HTR1A (0.43) | KMT2AGAAHTR2AMAPTCYP1A2 | |
| SCHEMBL8168722 | 0.78 | EGFR (0.48) | KMT2AGAAEGFRHTR2AMAPT | |
| SCHEMBL7926481 | 0.77 | HTR1A (0.46) | POLLKMT2AHTR2ACYP1A2MEN1 | |
| SCHEMBL11978323 | 0.75 | KDM4E (0.41) | KMT2AGAAMAPTCYP1A2CA1 | |
| SCHEMBL9309831 | 0.74 | ACHE (0.49) | POLLKMT2AGAACYP1A2CA1 | |
| SCHEMBL9441282 | 0.73 | MTNR1A (0.44) | TAS1R3TAS1R1TAS1R2POLLKMT2A | |
| SCHEMBL24650908 | 0.71 | DRD2 (0.42) | MAPTCYP1A2CA1CA2DRD2 | |
| SCHEMBL11957274 | 0.71 | CYP1A2 (0.38) | KMT2AGAAMAPTCYP1A2CA1 | |
| SCHEMBL11363652 | 0.70 | CYP1A2 (0.48) | POLLKMT2AGAAEGFRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5491236-A | NERVOUS SYTEM DISORDERS | THE UPJOHN COMPANY (US) | 1996-02-13 | — | — | US | disclosed |