Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.52 |
| ▸ | RARG | P13631 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765607 | 0.71 | ALDH1A1 (0.51) | RARARARGRARBALDH1A1MAPK1 | |
| SCHEMBL30488585 | 0.70 | ALOX5 (0.55) | ALDH1A1MAPK1CA12CA2CA9 | |
| SCHEMBL28804341 | 0.70 | ALDH1A1 (0.50) | RARARARGRARBALDH1A1MAPK1 | |
| SCHEMBL22331120 | 0.70 | RARA (0.46) | RARARARGRARBALDH1A1MAPK1 | |
| SCHEMBL4687524 | 0.69 | ALOX5 (0.45) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL31490849 | 0.69 | ALOX5 (0.45) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL23175286 | 0.68 | ALDH1A1 (0.47) | RARARARGRARBALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8826053 | 0.67 | ALOX5 (0.44) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL619634 | 0.67 | MAPK1 (0.78) | ALDH1A1MAPK1SRD5A2TSHRMAPT | |
| Piperonylic Acid SCHEMBL31119409 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPK1SRD5A2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663194-A | SCHIZOPHRENIA | WYETH | 1997-09-02 | — | — | US | disclosed |