Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901664 | 0.92 | SMN1; SMN2 (0.39) | ALDH1A1LMNAMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL8113240 | 0.91 | LMNA (0.36) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL30416435 | 0.86 | CA2 (0.34) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL64266 | 0.86 | CA2 (0.34) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| Diclosulam SCHEMBL2231960 | 0.85 | CA2 (0.33) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL9066675 | 0.84 | ACLY (0.38) | MAPK1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8902858 | 0.83 | SMN1; SMN2 (0.35) | LMNAMAPK1KMT2ASMN1; SMN2KAT6A | |
| SCHEMBL8848603 | 0.83 | WDR5 (0.42) | MAPTALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL8107121 | 0.82 | CCR4 (0.35) | ALDH1A1LMNAKMT2ATSHRPOLB | |
| Pyrimidine SCHEMBL27866314 | 0.82 | SCN9A (0.33) | MAPTALDH1A1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |