Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113251 | 0.91 | LMNA (0.37) | SMN1; SMN2LMNATSHRKMT2AGAA | |
| SCHEMBL8901664 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATSHRKMT2AGAA | |
| SCHEMBL910274 | 0.90 | GAA (0.42) | SMN1; SMN2TSHRKMT2AGAAMAPK1 | |
| SCHEMBL9066675 | 0.83 | ACLY (0.38) | SMN1; SMN2TSHRKMT2AGAAMAPK1 | |
| SCHEMBL30416435 | 0.83 | CA2 (0.34) | LMNATSHRKMT2AMAPK1SCN9A | |
| SCHEMBL64266 | 0.83 | CA2 (0.34) | LMNATSHRKMT2AMAPK1SCN9A | |
| SCHEMBL8901668 | 0.83 | MAPT (0.35) | SMN1; SMN2KAT6ALMNATSHRKMT2A | |
| Diclosulam SCHEMBL2231960 | 0.83 | CA2 (0.33) | LMNATSHRKMT2AMAPK1SCN9A | |
| SCHEMBL8113170 | 0.82 | TSHR (0.39) | TSHR | |
| SCHEMBL8848603 | 0.82 | WDR5 (0.42) | LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |
| US-5677594-A | ELECTROLUMINESCENT THIN FILM COMPRISING A SULFIDES OR A SELENIDES OF ALKALINE EARTH METAL AND ALUMINUM, INDIUM OR GALLIUM; MULTICOLOR PANELS | BANK OF AMERICA, N.A. | 1997-10-14 | — | — | US | disclosed |