SCHEMBL8904124

SCHEMBL8904124

C[Si](C)(C)Oc1ccc([NH])cc1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4763549 0.86 CA1 (0.39) CA12CA1CA2CA7CA9
SCHEMBL17881929 0.78 ESR2 (0.39) CA12CA1CA2CA7CA9
SCHEMBL9714337 0.78 ESR2 (0.39) CA12CA1CA2CA7CA9
SCHEMBL9115160 0.78 ALDH1A1 (0.41)
SCHEMBL2016960 0.76 ACHE (0.50) CA1CA2CA7CA9
SCHEMBL11233031 0.76 CA1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL3482956 0.74 APP (0.39) CA1CA2CA9
SCHEMBL11233025 0.74 CA12 (0.30) CA12CA1CA2CA7CA9
SCHEMBL197410 0.74 LMNA (0.42) CA1CA2CA9
SCHEMBL4677123 0.74 CA12 (0.30) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656264-A ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE SANSYO SEIYAKU CO., LTD. (JP) 1997-08-12 US disclosed
EP-0540854-A2 Preparation for promoting hair growth Sansho Seiyaku Co., Ltd. (JP) 1993-05-12 EP disclosed