SCHEMBL3482956

SCHEMBL3482956

C[Si](C)(C)Oc1ccc(I)cc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 14/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HDAC8 Q9BY41 1/20 0.33
NPBWR1 P48145 1/20 0.32
MCHR1 Q99705 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4763549 0.86 CA1 (0.39) CA1CA2CA9
SCHEMBL9714337 0.78 ESR2 (0.39) CA1CA2CA9
SCHEMBL9115160 0.78 ALDH1A1 (0.41)
SCHEMBL17881929 0.78 ESR2 (0.39) CA1CA2CA9
SCHEMBL1118830 0.77 PREP (0.50) APPCA1CA2CA9
SCHEMBL2016960 0.76 ACHE (0.50) CA1CA2CA9
SCHEMBL11233031 0.76 CA1 (0.61) CA1CA2CA9
SCHEMBL4677123 0.74 CA12 (0.30) CA1CA2CA9
SCHEMBL11233025 0.74 CA12 (0.30) CA1CA2CA9
SCHEMBL8904124 0.74 CA12 (0.30) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460111-B1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS EASTMAN KODAK CO (US) 1993-12-08 EP claimed
EP-0460111-A1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS. EASTMAN KODAK CO (US) 1991-12-11 EP claimed
US-4965361-A CATALYTIC REACTION OF 4-SUBSTITUTED ARYL IODIDE WITH OLEFIN IN ESTER SOLVENT EASTMAN KODAK COMPANY (US) 1990-10-23 US claimed
EP-0388322-A1 Preparation of 4-substituted aryl olefins EASTMAN KODAK COMPANY (US) 1990-09-19 EP claimed
WO-1990009973-A1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS EASTMAN KODAK COMPANY (US) 1990-09-07 WO claimed
EP-2121647-B1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS UNIV BARI (IT) 2014-09-24 EP disclosed
US-8461354-B2 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2013-06-11 US disclosed
US-8461354-B2 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2013-06-11 US disclosed
US-8461354-B2 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2013-06-11 US disclosed
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2010-06-10 US disclosed
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2010-06-10 US disclosed
EP-2121647-A1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS Universita' Degli Studi di Bari (IT) 2009-11-25 EP disclosed
WO-2008096239-A1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS UNIVERSITA' DEGLI STUDI DI BARI (IT) 2008-08-14 WO disclosed
EP-0460111-B1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS EASTMAN KODAK CO (US) 1993-12-08 EP disclosed
EP-0460111-A1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS. EASTMAN KODAK CO (US) 1991-12-11 EP disclosed
US-4965361-A CATALYTIC REACTION OF 4-SUBSTITUTED ARYL IODIDE WITH OLEFIN IN ESTER SOLVENT EASTMAN KODAK COMPANY (US) 1990-10-23 US disclosed
EP-0388322-A1 Preparation of 4-substituted aryl olefins EASTMAN KODAK COMPANY (US) 1990-09-19 EP disclosed
WO-1990009973-A1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS EASTMAN KODAK COMPANY (US) 1990-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors TPR, TTR, TRPA1 APP 72/4885CA1 3551/4885CA2 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.