Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 9/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905970 | 0.94 | PPARG (0.41) | GPR119PPARG | |
| SCHEMBL8906575 | 0.93 | AGTR2 (0.41) | PPARG | |
| SCHEMBL8906411 | 0.83 | GPR119 (0.38) | GPR119CYP1A2MEN1LMNAKMT2A | |
| SCHEMBL8906956 | 0.81 | ALDH1A1 (0.44) | PPARGDHODHMEN1LMNAKMT2A | |
| SCHEMBL8905734 | 0.80 | GPR119 (0.42) | GPR119MEN1KMT2A | |
| SCHEMBL8905936 | 0.76 | GPR119 (0.35) | GPR119 | |
| SCHEMBL8905700 | 0.76 | PPARG (0.50) | PPARG | |
| SCHEMBL8906316 | 0.75 | PPARG (0.44) | PPARGDHODH | |
| SCHEMBL9094676 | 0.75 | PPARG (0.62) | PPARG | |
| SCHEMBL8906593 | 0.74 | GPR119 (0.41) | GPR119PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |