Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 7/20 | 0.55 |
| ▸ | MMP8 | P22894 | 6/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906141 | 0.86 | MMP8 (0.55) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL8905827 | 0.84 | MMP2 (0.52) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL8904930 | 0.78 | PTPN2 (0.51) | MMP9MMP8MMP2CTSSCTSK | |
| SCHEMBL8906233 | 0.76 | MMP2 (0.46) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL760986 | 0.74 | MMP2 (0.60) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL13956910 | 0.73 | KMT2A (0.54) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL5556628 | 0.72 | CTSS (0.76) | MMP9MMP8MMP2TACR1CTSS | |
| SCHEMBL13494599 | 0.72 | CTSS (0.46) | CTSSCTSKMMP1 | |
| SCHEMBL6318014 | 0.72 | CTSS (0.46) | CTSSCTSKMMP1 | |
| SCHEMBL28740722 | 0.72 | CTSS (0.46) | CTSSCTSKMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |