Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906144 | 0.85 | ALOX5 (0.43) | ALOX5MMP2MMP9MMP8CMA1 | |
| SCHEMBL8906233 | 0.81 | MMP2 (0.46) | MMP2MMP9MMP8MAPTMAPK8 | |
| SCHEMBL8906777 | 0.76 | DPP4 (0.38) | — | |
| SCHEMBL5690336 | 0.69 | ALOX5 (0.59) | ALOX5CMA1MAPTMAPK8JUN | |
| SCHEMBL8906236 | 0.69 | MMP9 (0.55) | MMP2MMP9MMP8SMN1; SMN2CASP3 | |
| SCHEMBL8906136 | 0.68 | MMP2 (0.47) | MMP2MMP9MMP8MAPTMAPK8 | |
| SCHEMBL13494674 | 0.66 | CTSS (0.46) | HPGDGAA | |
| SCHEMBL5557511 | 0.66 | MMP2 (0.54) | MMP2MMP9MMP8MAPTMAPK8 | |
| SCHEMBL8906770 | 0.65 | CYP19A1 (0.41) | MMP2MMP9MMP8 | |
| SCHEMBL13494599 | 0.64 | CTSS (0.46) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |