Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187909 | 0.85 | CYP3A4 (0.51) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL31726055 | 0.84 | KDM4E (0.47) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL348929 | 0.78 | L3MBTL1 (0.49) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL29501305 | 0.78 | L3MBTL1 (0.49) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL13863649 | 0.77 | KDM4E (0.45) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL14070591 | 0.77 | TDP1 (0.33) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL349002 | 0.76 | CA12 (0.57) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL6536424 | 0.75 | HK2 (0.53) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL6014051 | 0.75 | TDP1 (0.67) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL2172500 | 0.74 | ERN1 (0.54) | TDP1L3MBTL1KDM4EPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029901-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2013-01-31 | — | — | US | disclosed |
| US-20130029901-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2013-01-31 | — | — | US | disclosed |
| US-20130029901-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2013-01-31 | — | — | US | disclosed |
| US-20120083440-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2012-04-05 | — | — | US | disclosed |
| US-20120083440-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2012-04-05 | — | — | US | disclosed |
| US-20120083440-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | Pradama, Inc. | 2012-04-05 | — | — | US | disclosed |
| US-8071575-B2 | Methods and compounds for the targeted delivery of agents to bone for interaction therewith | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071575-B2 | Methods and compounds for the targeted delivery of agents to bone for interaction therewith | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071575-B2 | Methods and compounds for the targeted delivery of agents to bone for interaction therewith | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2011-12-06 | — | — | US | disclosed |
| EP-2114415-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2009-11-11 | — | — | EP | disclosed |
| US-20080221070-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION | 2008-09-11 | — | — | US | disclosed |
| US-20080221070-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION | 2008-09-11 | — | — | US | disclosed |
| WO-2008103951-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008103951-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC (US) | 2008-08-28 | — | — | WO | disclosed |
| US-20070161710-A1 | BONE TARGETING COMPOUNDS FOR DELIVERING AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION | 2007-07-12 | — | — | US | disclosed |
| US-20070161710-A1 | BONE TARGETING COMPOUNDS FOR DELIVERING AGENTS TO BONE FOR INTERACTION THEREWITH | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION | 2007-07-12 | — | — | US | disclosed |
| EP-1697302-A1 | COMPOUNDS FOR DIAGNOSIS, TREATMENT AND PREVENTION OF BONE INJURY AND METABOLIC DISORDERS | University of Louisville Research Foundation (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005066114-A1 | COMPOUNDS FOR DIAGNOSIS, TREATMENT AND PREVENTION OF BONE INJURY AND METABOLIC DISORDERS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050143366-A1 | Compounds for diagnosis, treatment and prevention of bone injury and metabolic disorders | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2000066613-A1 | BONE TARGETING AGENTS FOR OSTEOPOROSIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221070-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | SHBG, ESRRA, ESRRG | TDP1 4589/4885L3MBTL1 4641/4885KDM4E 2439/4885 |
| US-20050143366-A1 | Compounds for diagnosis, treatment and prevention of bone injury and metabolic disorders | SOST, BMP2, BMP4 | TDP1 2990/4885L3MBTL1 2383/4885KDM4E 4037/4885 |
| US-20120083440-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | BMP2, SOST, BMP4 | TDP1 4079/4885L3MBTL1 3761/4885KDM4E 3426/4885 |
| US-20130029901-A1 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH | BMP2, SOST, BMP4 | TDP1 4079/4885L3MBTL1 3761/4885KDM4E 3426/4885 |
| US-20070161710-A1 | BONE TARGETING COMPOUNDS FOR DELIVERING AGENTS TO BONE FOR INTERACTION THEREWITH | SOST, BMP2, BMP6 | TDP1 4749/4885L3MBTL1 2879/4885KDM4E 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.