Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910129 | 0.82 | S1PR1 (0.38) | PTPN1S1PR1S1PR3SLC22A12 | |
| SCHEMBL8482791 | 0.82 | HRH3 (0.34) | PTPN1S1PR1S1PR3 | |
| SCHEMBL8911110 | 0.80 | LTB4R2 (0.34) | PTPN1 | |
| SCHEMBL8485604 | 0.73 | MAOB (0.37) | S1PR1 | |
| SCHEMBL8484313 | 0.67 | PPARG (0.33) | S1PR1 | |
| SCHEMBL8482788 | 0.64 | PTPN1 (0.34) | PTPN1SLC22A12 | |
| SCHEMBL8487337 | 0.64 | CYP2A6 (0.40) | — | |
| SCHEMBL9842996 | 0.63 | AGTR1 (0.51) | — | |
| SCHEMBL8911282 | 0.63 | LTB4R2 (0.34) | — | |
| SCHEMBL8482148 | 0.63 | LTB4R2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |