Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGB | P02675 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536893 | 0.84 | MAPT (0.52) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL8911552 | 0.77 | SMN1; SMN2 (0.36) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL8150303 | 0.73 | MAPT (0.41) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL9434365 | 0.72 | FGB (0.42) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL9215754 | 0.72 | TSHR (0.37) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL1388444 | 0.69 | FGB (0.38) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL7963227 | 0.69 | LMNA (0.36) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL9434368 | 0.68 | SMN1; SMN2 (0.36) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL9434910 | 0.67 | HRH3 (0.37) | FGBMAPTLMNAHIF1AHSP90AA1 | |
| SCHEMBL7966334 | 0.67 | KDM4E (0.36) | FGBMAPTLMNAHIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |