SCHEMBL8910940

SCHEMBL8910940

C=CCN(CC=C)c1ccc2c[c]ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.34
CRHR1 P34998 1/20 0.33
CHKA P35790 1/20 0.32
TERT O14746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297157 0.80 TERT (0.52) TERT
SCHEMBL10935728 0.78 INSR (0.46) DHFRCHKA
SCHEMBL297148 0.75 APP (0.45) CRHR1TERT
SCHEMBL564593 0.75 CYP2A6 (0.46) DHFRCRHR1CHKATERT
SCHEMBL28594401 0.75 ALDH1A1 (0.34) DHFRCRHR1CHKATERT
SCHEMBL564592 0.75 CHKA (0.34) DHFRCRHR1CHKATERT
SCHEMBL564591 0.75 CHKA (0.34) DHFRCRHR1CHKATERT
SCHEMBL297143 0.74 APP (0.41) TERT
SCHEMBL252675 0.73 CHKA (0.43) CHKA
SCHEMBL18394267 0.71 XDH (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5598005-A Non-destructive method for determining the extent of cure of a polymerizing material and the solidification of a thermoplastic polymer based on wavelength shift of fluroescence THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE COMMERCE (US) 1997-01-28 US claimed
CN-103796999-B Luminescent substrates for luciferase enzymes UNIV ELECTRO COMMUNICATIONS 2015-07-22 CN disclosed
US-8962854-B2 Luminescent substrate for luciferase THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) 2015-02-24 US disclosed
US-20140221665-A1 LUMINESCENT SUBSTRATE FOR LUCIFERASE THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) 2014-08-07 US disclosed
EP-2754657-A1 LUMINESCENT SUBSTRATE FOR LUCIFERASE The University of Electro-Communications (JP) 2014-07-16 EP disclosed
CN-103796999-A Luminescent substrates for luciferase enzymes UNIV ELECTRO COMMUNICATIONS 2014-05-14 CN disclosed
WO-2013027770-A1 LUMINESCENT SUBSTRATE FOR LUCIFERASE 国立大学法人電気通信大学 (JP) 2013-02-28 WO disclosed
US-5598005-A Non-destructive method for determining the extent of cure of a polymerizing material and the solidification of a thermoplastic polymer based on wavelength shift of fluroescence THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE COMMERCE (US) 1997-01-28 US disclosed