Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821817 | 0.98 | CHKA (0.42) | CHKACYP1A2 | |
| SCHEMBL6775781 | 0.88 | ALDH1A1 (0.38) | CHKA | |
| SCHEMBL851567 | 0.83 | CHKA (0.50) | CHKACYP1A2 | |
| SCHEMBL3290812 | 0.78 | PYCR1 (0.35) | — | |
| SCHEMBL4047348 | 0.77 | ESR1 (0.38) | CYP1A2 | |
| SCHEMBL7162904 | 0.76 | CHKA (0.46) | CHKACYP1A2 | |
| SCHEMBL83762 | 0.76 | CHKA (0.46) | CHKACYP1A2 | |
| SCHEMBL6466250 | 0.76 | CHKA (0.46) | CHKACYP1A2 | |
| SCHEMBL6692403 | 0.76 | CHKA (0.46) | CHKACYP1A2 | |
| SCHEMBL11032897 | 0.76 | CHKA (0.46) | CHKACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301725-A1 | AMINE SYNERGISTS WITH UV-A ABSORPTION | Sun Chemical Corporation (US) | 2024-01-10 | — | — | EP | claimed |
| US-RE49735-E1 | Oxazolidinones as modulators of MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-28 | — | — | US | claimed |
| EP-4232040-A1 | COMBINATION THERAPY OF PD-1 AXIS BINDING ANTAGONISTS AND LRRK2 INHITIBORS | F. Hoffmann-La Roche AG (CH) | 2023-08-30 | — | — | EP | claimed |
| WO-2023118482-A1 | AMINE SYNERGISTS WITH UV-A ABSORPTION | SUN CHEMICAL CORPORATION (US) | 2023-06-29 | — | — | WO | claimed |
| US-11369584-B2 | Andrographolide derivatives and method of using the same for treatment or prevention of fibrosis | ZHENGZHOU UNIVERSITY (CN) | 2022-06-28 | — | — | US | claimed |
| WO-2022084210-A1 | COMBINATION THERAPY OF PD-1 AXIS BINDING ANTAGONISTS AND LRRK2 INHITIBORS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-04-28 | — | — | WO | claimed |
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | claimed |
| US-20210253587-A1 | TRIAZOLINEDIONE ADDUCT, METHOD FOR PRODUCING TRIAZOLINEDIONE ADDUCT, METHOD FOR PRODUCING ENE COMPOUND, AND METHOD FOR ANALYZING ENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2021-08-19 | — | — | US | claimed |
| US-20210122721-A1 | BIS-PROPENAMIDE COMPOUNDS AND METHODS OF TREATING CANCER | KING ABDULAZIZ UNIVERSITY (SA) | 2021-04-29 | — | — | US | claimed |
| EP-3758706-A2 | WEE1 KINASE INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME | The Regents Of The University Of Colorado (US) | 2021-01-06 | — | — | EP | claimed |
| EP-0010652-A1 | 4-Chlorooxazoles, method for their preparation and their use in photoconductive coatings in electrophotography and as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-14 | — | — | EP | claimed |
| US-4192677-A | ELECTROGRAPHIC CHARGE TRANSFER COMPOUNDS | RICOH CO., LTD. (JP) | 1980-03-11 | — | — | US | claimed |
| US-4160671-A | ESTER OR AMIDE OF AN O-NAPHTHOQUINONE DIAZIDE SULFONIC ACID, ORGANIC DYE, HALOGEN-CONTAINING DERIVATIVE OF PYRONE OR TRIAZINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-10 | — | — | US | claimed |
| US-4145215-A | PHOTOCONDUCTIVE PIGMENTS | EASTMAN KODAK COMPANY (US) | 1979-03-20 | — | — | US | claimed |
| US-RE29748-E | TRIHALOMETHYL COMPOUND AND BIS(DIALKYLAMINOPHENYL)ALKENE | HORIZONS INCORPORATED A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1978-08-29 | — | — | US | claimed |
| US-4061637-A | CNS, CARDIOVASCULAR, ANTIINFLAMMATORY, ADRENOLYTIC, ANTIULCER | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-12-06 | — | — | US | claimed |
| US-3967965-A | HETEROCYCLIC UREAS | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-06 | — | — | US | claimed |
| US-RE28789-E | ETHYLENICALLY UNSATURATED MONOMER; RADIATION ABSORBER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-3951654-A | CHARGE TRANSPORT SENSITIZER | XEROX CORPORATION (US) | 1976-04-20 | — | — | US | claimed |
| US-3944417-A | Process for the electrophotographic production of printing plates | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-03-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122721-A1 | BIS-PROPENAMIDE COMPOUNDS AND METHODS OF TREATING CANCER | APC, CCNE1, CCNI | CHKA 320/4885CYP1A2 141/4885 |
| US-20210253587-A1 | TRIAZOLINEDIONE ADDUCT, METHOD FOR PRODUCING TRIAZOLINEDIONE ADDUCT, METHOD FOR PRODUCING ENE COMPOUND, AND METHOD FOR ANALYZING ENE COMPOUND | NR2E1, AR, NR5A2 | CHKA 2676/4885CYP1A2 100/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | CHKA 2822/4885CYP1A2 2177/4885 |
| US-11369584-B2 | Andrographolide derivatives and method of using the same for treatment or prevention of fibrosis | MMP1, CYP27A1, PYGL | CHKA 3281/4885CYP1A2 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.