Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466474 | 0.81 | LMNA (0.60) | CA12CA9CA1CA2HDAC6 | |
| SCHEMBL6821033 | 0.76 | PTPN1 (0.46) | ALDH1A1PTPN1PTPN6PTPN11CYP3A4 | |
| SCHEMBL22922181 | 0.73 | CYP4F2 (0.59) | CA12CA9IDO1ALDH1A1LMNA | |
| SCHEMBL2303459 | 0.73 | CA2 (0.65) | CA12CA9CA1CA2IDO1 | |
| SCHEMBL28147719 | 0.73 | BMP1 (0.50) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL15226692 | 0.73 | HIF1A (0.69) | CA12CA9CA1CA2HDAC6 | |
| SCHEMBL8142192 | 0.73 | ALDH1A1 (0.50) | IDO1HDAC6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14733281 | 0.73 | CYP4F2 (0.49) | CA12CA9IDO1ALDH1A1LMNA | |
| SCHEMBL5567796 | 0.72 | ADRB2 (0.51) | CA12CA9IDO1ALDH1A1LMNA | |
| SCHEMBL6818574 | 0.72 | SMN1; SMN2 (0.52) | CA1CA2ALDH1A1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |