Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 3/20 | 0.32 |
| ▸ | RHOA | P61586 | 3/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912916 | 0.75 | DDR1 (0.38) | CES2GAAP2RX1HDAC3HDAC6 | |
| SCHEMBL23091832 | 0.75 | CES2 (0.64) | CES2GAATACR1PTPN1P2RX1 | |
| SCHEMBL8913304 | 0.70 | VNN1 (0.40) | CES2GAAPTPN1GSK3BHDAC3 | |
| SCHEMBL8911364 | 0.70 | DDR1 (0.40) | CES2GAAP2RX1HDAC3HDAC6 | |
| SCHEMBL8912083 | 0.70 | GPR139 (0.31) | — | |
| SCHEMBL4944429 | 0.70 | CES2 (0.57) | CES2GAATACR1PTPN1P2RX1 | |
| SCHEMBL8910968 | 0.70 | CES2 (0.39) | CES2PTPN1LMNAMAPT | |
| SCHEMBL29115453 | 0.69 | CES2 (0.55) | CES2GAATACR1PTPN1P2RX1 | |
| SCHEMBL23091848 | 0.69 | CES2 (0.55) | CES2GAATACR1PTPN1P2RX1 | |
| SCHEMBL630414 | 0.68 | PTPN1 (0.66) | CES2GAATACR1PTPN1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |