SCHEMBL8913718

SCHEMBL8913718

O=C(O)c1ccc(C(=O)O)c2c1CCOc1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NOTUM Q6P988 2/20 0.41
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALPL P05186 1/20 0.39
MYC P01106 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
FABP4 P15090 3/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
WDR5 P61964 1/20 0.37
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496918 0.77 SLC9A1 (0.43) ALDH1A1KDM4EFABP4
SCHEMBL27706294 0.74 NOTUM (0.47) MEN1KMT2ANOTUMALDH1A1KDM4E
SCHEMBL134045 0.73 XDH (0.44) ALDH1A1KDM4EHSD17B10LMNAMAPT
Chromanone SCHEMBL4474722 0.70 GRM5 (0.55) MEN1KMT2ANOTUMALDH1A1KDM4E
SCHEMBL31707347 0.70 ALDH1A1 (0.41) ALDH1A1KDM4EMYCL3MBTL1LMNA
SCHEMBL9188696 0.69 SMN1; SMN2 (0.38) ALDH1A1KDM4EHSD17B10FABP4HPGD
SCHEMBL1652930 0.68 ALDH1A1 (0.57) MEN1KMT2AALDH1A1KDM4EHSD17B10
SCHEMBL30949546 0.68 TSHR (0.39) ALDH1A1KDM4EHSD17B10L3MBTL1MAPT
SCHEMBL29091574 0.68 G6PD (0.38) MEN1KMT2AALDH1A1KDM4EHSD17B10
SCHEMBL984633 0.68 SMN1; SMN2 (0.44) MEN1KMT2AALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5614342-A Methods for preparing cocrystals of titanyl fluorophthalocyanines and unsubstituted titanyl phthalocyanine, electrophotographic elements, and titanyl phthalocyanine compositions EASTMAN KODAK COMPANY (US) 1997-03-25 US disclosed
US-5500317-A DICYANO-SULFONE COMPOUND EASTMAN KODAK COMPANY (US) 1996-03-19 US disclosed
WO-1992022856-A1 PHOTOELECTROGRAPHIC IMAGING WITH A MULTI-ACTIVE ELEMENT CONTAINING NEAR-INFRARED SENSITIZING PIGMENTS EASTMAN KODAK COMPANY (US) 1992-12-23 WO disclosed
EP-0409160-A2 Electrophotographic recording elements containing a combination of photoconductive perylene materials EASTMAN KODAK COMPANY (US) 1991-01-23 EP disclosed
EP-0374838-A2 Electrophotographic elements containing certain anthraquinone derivatives as electron-transport agents EASTMAN KODAK COMPANY (US) 1990-06-27 EP disclosed
EP-0253169-A2 Pigments, photoconductive elements sensitive to infrared radiation and a method of making EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-01-20 EP disclosed
US-4477548-A WEAR RESISTANT, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1984-10-16 US disclosed